Abstract #2363

Long term evaluation of ventricular volume change associated with shunt-responsiveness in idiopathic normal pressure hydrocephalus

Romtheera Kamronritthisorn¹, Kritdipha Ningunha², Peeratat Suppapanya¹, Sunee Bovonsunthonchai³, Doonyaporn Wongsawaeng ¹, Yudthaphon Vichianin⁴, Theerapol Witthiwej⁵, Weerasak Muangpaisan⁶, Panida Charnchaowanish¹, Siriwan Piyapittayanan¹, Orasa Chawalparit¹, and Chanon Ngamsombat¹

¹Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ²Department of TELE-Radiology, Bangkok Hospital Headquarters, Bangkok, Thailand, ³Faculty of Physical Therapy, Mahidol University, Bangkok, Thailand, ⁴Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand, ⁵Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ⁶Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Shunt surgery is an effective treatment for iNPH, however some patients showed unsustainable response. We investigated how reduction of ventricular size after shunt surgery correlated with clinical outcome, as potential predictor of long-term shunt responsiveness using automated segmentation of ventricular volume from T1W sequence. A reduction of ventricular volume is found to negatively correlate with improved cognition. These findings might be one of helpful imaging predictors for the shunt responders in iNPH.

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