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Abstract #2363

Long term evaluation of ventricular volume change associated with shunt-responsiveness in idiopathic normal pressure hydrocephalus

Romtheera Kamronritthisorn1, Kritdipha Ningunha2, Peeratat Suppapanya1, Sunee Bovonsunthonchai3, Doonyaporn Wongsawaeng 1, Yudthaphon Vichianin4, Theerapol Witthiwej5, Weerasak Muangpaisan6, Panida Charnchaowanish1, Siriwan Piyapittayanan1, Orasa Chawalparit1, and Chanon Ngamsombat1
1Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Department of TELE-Radiology, Bangkok Hospital Headquarters, Bangkok, Thailand, 3Faculty of Physical Therapy, Mahidol University, Bangkok, Thailand, 4Department of Radiological Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand, 5Division of Neurosurgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 6Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Shunt surgery is an effective treatment for iNPH, however some patients showed unsustainable response. We investigated how reduction of ventricular size after shunt surgery correlated with clinical outcome, as potential predictor of long-term shunt responsiveness using automated segmentation of ventricular volume from T1W sequence. A reduction of ventricular volume is found to negatively correlate with improved cognition. These findings might be one of helpful imaging predictors for the shunt responders in iNPH.

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