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Abstract #2378

Water content for anatomical imaging with layer resolution at 7T

Ana-Maria Oros-Peusquens1, Jonas Kielmann1, and N. Jon Shah1,2,3,4
1INM-4, Research Centre Juelich, Juelich, Germany, 2Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany, 3INM-11, JARA, Research Centre Juelich, Juelich, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Germany

An increasing number of structural studies attempt identification of distinct structural regions based on their layer signature. Interestingly, water content quantitative contrast is little used in these attempts, despite being a fundamental contrast in MRI, based on the proton equilibrium magnetisation, and closely reflecting cell density on which modern cytoarchitectonic studies are based. In this contribution, we demonstrate the usefulness of water content contrast at 7T and propose it for layer-related studies and high-resolution brain anatomy.

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