Meeting Banner
Abstract #2379

Vascular origins of low-frequency oscillations in cerebrospinal fluid resting-state fMRI signal: Interpretation using photoplethysmography

Ahmadreza Attarpour1, James Ward2, and J. Jean Chen1,2
1Medical Biophysics, University of Toronto, Toronto, ON, Canada, 2Rotman Research Institute, Baycrest, Toronto, ON, Canada

Due to its cardiogenic constituents, the cerebrospinal fluid (CSF) contribution to resting-state functional MRI (rs-fMRI) has been used for denoising. Recently, it has become increasingly used for characterizing CSF flow and glymphatic flow. However, the association between CSF and vascular oscillations in rs-fMRI remains to be fully understood. In this study, we quantify the relationship between rs-fMRI fluctuation in different CSF compartments and photoplethysmography (PPG) recordings, focusing on the frequency band around 0.1 Hz. We also quantify their relationship between the rs-fMRI signals (in CSF, tissue and vasculature) and other vascular measures derived from PPG traces.

This abstract and the presentation materials are available to members only; a login is required.

Join Here