We conducted water peak MRS without water suppression, in which the water peak itself is evaluated, to determine if the water peak is altered by the existence of solutes and to evaluate the feasibility of water peak MRS for detecting pathologic changes in CSF. The water peaks were modified by the solute concentrations of NaCl, Glu, and Alb. Differences in water peaks were observed among the CSF phantom simulating normal CSF, CSF with bacterial meningitis, and CSF with obstruction of the subarachnoid space.
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