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Abstract #2385

Feasibility of water peak MRS without water suppression for the evaluation of cerebrospinal fluid

Toshiaki Taoka1,2, Rintaro Ito1,2, Rei Nakamichi2, Takashi Abe2, Toshiki Nakane2, Hisashi Kawai2, Mayuko Sakai3, and Shinji Naganawa2
1Department of Innovative Biomedical Visualization (iBMV), Nagoya University, Nagoya, Japan, 2Radiology, Nagoya University, Nagoya, Japan, 3Canon Medical Systems Corporation, Otawara, Japan

We conducted water peak MRS without water suppression, in which the water peak itself is evaluated, to determine if the water peak is altered by the existence of solutes and to evaluate the feasibility of water peak MRS for detecting pathologic changes in CSF. The water peaks were modified by the solute concentrations of NaCl, Glu, and Alb. Differences in water peaks were observed among the CSF phantom simulating normal CSF, CSF with bacterial meningitis, and CSF with obstruction of the subarachnoid space.

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