A multiparametric renal MRI scan protocol was employed to characterise the impact of renal fibrosis on tissue relaxation properties. The study recruited patients with moderate renal dysfunction (CKD stage 3, eGFR between 30 and 60 ml/min/1.73 m2) with biopsy-proven fibrosis and age-matched healthy volunteers. Statistically significant differences in kidney cortical native T1 and T2 were observed between patients and controls, ascribed to tissue microstructural changes associated with the mild fibrosis observed in the patient group.
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