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Abstract #2529

Value of quantitative susceptibility mapping for detecting renal fibrosis of early diabetic nephropathy in type 2 diabetes

Jiayuan Shan1, Jinggang Zhang1, Jie Chen1, Wei Xing1, and Jilei Zhang2
1Radiology, Third Affiliated Hospital of Soochow University, Changzhou, China, 2Philips Healthcare, Shanghai, China

The purpose was to explore if quantitative susceptibility mapping (QSM) can assess renal fibrosis about early diabetic nephropathy (DN) in type 2 diabetes (T2D). 32 patients with early DN in T2D were included in the study to evaluate the potential clinical relevance of QSM. We found that susceptibility values of the medulla were statistically significant among different fibrosis. Susceptibility value of the medulla was highly correlated with estimated glomerular filtration rate (eGFR). QSM could serve as a quantitative biomarker to assess the renal fibrosis and monitor the treatment in patients with DN.

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