Abstract #2533

Renal hypoxia estimated by O2-inhalation T2* BOLD MRI: association with renal dysfunction and left ventricular remodeling in cardiomyopathy

Michinobu Nagao¹, Kiyoe Ando¹, Yasuhiro Goto¹, Isao Shiina¹, Kazuo Kodaira¹, Masami Yoneyama², Takashi Namiki², Atsushi Yamamoto¹, Eri Watanabe¹, Akiko Sakai¹, Risako Nakao¹, and Shuji Sakai¹

¹Tokyo Women's Medical University, Tokyo, Japan, ²Philips Japan, Tokyo, Japan

O2-inhalation T2*-BOLD MRI is a non-invasive imaging techniqueto evaluate renal oxygenation. This analysis revealed that renal hypoxia is strongly associated with renal dysfunction, and that early left ventricular remodeling in cardiomyopathy leads to renal hypoxia. This renal hypoxia image helps clarify chronic cardiorenal interaction and the effects of drugs for cardiorenal disease.

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