Abstract #2532

Evaluation of renal oxygenation and hemodynamics in patients with chronic kidney disease by BOLD-MRI and intrarenal Doppler ultrasonography

Jing Yang ¹, Shuohui Yang ², Zheng He³, Mengxiao Liu⁴, and Caixia Fu⁵

¹Nephrology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, ²Radiology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, ³Ultrasonography, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, ⁴MR Scientific Marketing, Siemens Healthcare, Shanghai, China, ⁵MR Applications Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

The purpose of this study was to observe the alteration of renal oxygenation and renal hemodynamics in CKD patients using blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) and intrarenal Doppler ultrasonography (IDU). The result showed that renal oxygenation and blood flow velocities declined as the CKD stage progressed. The BOLD-MRI and IDU techniques were able to dynamically evaluate intrarenal oxygenation and hemodynamics changes, respectively, in CKD patients. Combination these two techniques can detect the abnormalities associated with CKD stage sensitively.

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