Abstract #2531

Quantitative T1 and R2* mapping in the evaluation of renal function in chronic kidney disease

Jiaxin Yan¹, Weiqiang Dou², Hongmei Gu¹, Xinquan Wang¹, Weiyin Vivian Liu², Huijian Lu¹, Ying Zhou¹, Xuejun Zhou¹, and LI Yuan¹

¹Affiliated Hospital of Nantong University, Nantong, China, ²GE Healthcare, MR Research China, Beijing, China

In this study, we explore the quantitative T1 and R2* mapping in theclassification on renal function in chronic kidney disease (CKD) . 146 CKD patients and 26 healthy volunteers（HVs）underwent T1 mapping and renal BOLD-MRI for R2* mapping. All CKD cases were divided into two groups according to the estimated glomerular filtration (eGFR)：mild renal impairment group and moderate to severe group.Clincal information were collected.Compared with HVs,the T1 and R2* values of renal cortex were significantly higher and were well correlated with renal function.Therefore,T1 mapping and BOLD-MRI derived R2* mapping might provide an effective method in assessing renal function.

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