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Abstract #2536

Evaluation of renal function in healthy volunteers and patients with chronic kidney disease by using APT weighted  imaging and R2* mapping

Ye Ju1, Ailian Liu1, Jiazheng Wang2, Wenjun Hu1, Changyu Du3, Lingli Qi3, Haoyang Jiang3, Xinmiao Bu1, Nan Wang1, and Peng Sun2
1First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare, Beijing, China, 3Dalian Medical University, Dalian, China

Amide proton transfer (APT) and mDixon - Quant techniques have been applied in clinical work, However, there was no study on the degree of renal damage in chronic kidney disease (CKD). We discussed the value of APT combined with R2* to assess the degree of renal damage. The AUC, sensitivity and specificity of APT combined R2* were 0.925, 88% and 100%, respectively. The combination of APT and R2* can improve the diagnostic ability of discriminating CKD from HVs, which has certain clinical application value.

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