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Abstract #2540

Ex-Vivo Renal Vascular Dominant Region Mapping using High Resolution 3D-T2w-MRI and Artery-Selective Contrast Injections in Porcine Kidneys

Nathan Sennesael1,2, Pieter R.E. De Backer3,4,5, Charlotte Debbaut4,6, Karel Decaestecker3,5, Pieter L.J. De Visschere2,7, Marijn M. Speeckaert8,9, Saar Vermijs4,5, Geert Villeirs2,7, and Pim Pullens1,2,7
1GIfMI, Ghent University, Ghent, Belgium, 2Diagnostic Sciences, Ghent University, Ghent, Belgium, 3Urology, Ghent University Hospital, Ghent, Belgium, 4IBiTech-bioMMeda, Ghent University, Ghent, Belgium, 5Human Structure and Repair, Ghent University, Ghent, Belgium, 6Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium, 7Radiology, Ghent University Hospital, Ghent, Belgium, 8Nephrology, Ghent University Hospital, Ghent, Belgium, 9Internal diseases and Paediatrics, Ghent University, Ghent, Belgium

During partial nephrectomy (PN), a trade-off between clamping arteries to assure optimal conditions for surgery and maximizing oxygenation to tissue unaffected by the tumor, has to be made. Knowledge of the anatomy of the renal vascular dominant regions, can help optimize this trade-off and thus has the potential to significantly improve PN interventions. We found that high resolution 3D-T2w-MRI scans in combination with artery-selective contrast injections is an effective alternative to ex-vivo kidney casting as it allows for 3D mapping of the renal vascular dominant regions and shows potential for segmentation of the renal vascular tree.

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