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Abstract #2541

T2 mapping in the dynamic evaluation of renal ischemia-reperfusion injury: an animal study

Jing Chen1, Jinggang Zhang1, Weiqiang Dou2, and Jie Chen1
1The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China, 2GE Healthcare, MR Research China, Beijing, Beijing, China

This study explored the relationship between the T2 value of the outer medulla and the pathological characteristics of renal ischemia reperfusion injury (IRI) in an animal model. T2 values of the outer medulla increased at 1 hour after IRI and decreased from 1 hour to 48 hours gradually. T2 values of the outer medulla were significantly correlated with pathological score of renal injury, especially with tubular epithelial edema. Based on the findings, T2 mapping might reflect the dynamic changes of renal IRI and be used to assess the renal IRI in the early stage.

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