Abstract #2542

The value of DKI in assessing the pathologic microstructural changes in the early stages of renal cold ischemia-reperfusion injuries

Yizhong Yuan¹, Jipan Xu¹, Yan Ren², Lihua Chen², Jinxia Zhu³, Robert Grimm⁴, and Wen Shen²

¹First Central Hospital Institute, Tianjin Medical University, Tianjin, China, ²Department of Radiology, Tianjin First Center Hospital, Tianjin, China, ³MR Collaboration, Siemens Healthcare, Beijing, China, ⁴MR Application development, Siemens Healthcare GmbH, Erlangen, Germany

This study investigated diffusion kurtosis imaging (DKI) values in evaluating the microstructural changes in the early stages of renal cold ischemia-reperfusion injuries (CIRIs). The results showed that both the mean diffusivity (MD) values and mean kurtosis (MK) values were negatively correlated with the pathologic scores, and the MK values showed more detailed microstructural changes than the MD values.

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