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Abstract #2543

Values of R2’ mapping on evaluation of renal ischemia-reperfusion injury:an experimental study

Qin Chen1, JingGang Zhang1, WeiQiang Dou2, Jie Chen1, and Wei Xing1
1The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China, 2GE Healthcare, MR Research, Beijing, China

Ischemia reperfusion injury (IRI) is the main factor that delays the recovery of the renal function and leads to the failure of treatment. To our knowledge, R2’ mapping as a quantitative MRI method may be helpful for assessment of IRI in the early stage. This study compared the R2’ values of outer medulla at different time points in a rabbit model and found significant differences between IRI group and control group. Meanwhile, significant correlation was also found between R2’ values and histopathological features. R2’ mapping can evaluate the dynamic changes of the outer medulla longitudinally.

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