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Abstract #2544

Intravoxel Incoherent Motion Imaging of Renal Cold Ischemia Reperfusion Injury in Rats

Yan Ren1, Lihua Chen1, Yizhong Yuan2, Jipan Xu2, Jinxia Zhu3, Robert Grimm4, and Wen Shen1
1Tianjin First Center Hospital, Tianjin, China, 2First Central Hospital Institute, Tianjin Medical University, Tianjin, China, 3MR collaborations, Siemens Healthcare Ltd., Beijing, China, 4Siemens Healthcare GmbH, Erlangen, Germany

The study evaluated the use of Intravoxel Incoherent Motion (IVIM) imaging to detect dynamic changes in renal microvascular characteristics during cold ischemia-reperfusion injuries (CIRIs). As previous studies have investigated warm ischemia-reperfusion injuries, we aimed to assess MR diffusion imaging in a renal CIRI Sprague Dawley rat model. Results showed that IVIM imaging is a sensitive tool to monitor changes in renal functional characteristics.

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