Abstract #2544

Intravoxel Incoherent Motion Imaging of Renal Cold Ischemia Reperfusion Injury in Rats

Yan Ren¹, Lihua Chen¹, Yizhong Yuan², Jipan Xu², Jinxia Zhu³, Robert Grimm⁴, and Wen Shen¹

¹Tianjin First Center Hospital, Tianjin, China, ²First Central Hospital Institute, Tianjin Medical University, Tianjin, China, ³MR collaborations, Siemens Healthcare Ltd., Beijing, China, ⁴Siemens Healthcare GmbH, Erlangen, Germany

The study evaluated the use of Intravoxel Incoherent Motion (IVIM) imaging to detect dynamic changes in renal microvascular characteristics during cold ischemia-reperfusion injuries (CIRIs). As previous studies have investigated warm ischemia-reperfusion injuries, we aimed to assess MR diffusion imaging in a renal CIRI Sprague Dawley rat model. Results showed that IVIM imaging is a sensitive tool to monitor changes in renal functional characteristics.

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