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Abstract #2607

Accelerating 3D variable-flip-angle T1 mapping: a prospective study based on SUPER-CAIPIRINHA

Fan Yang1, Jian Zhang2, Guobin Li2, Jiayu Zhu2, Xin Tang1, and Chenxi Hu1
1Institute of Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 2United Imaging Healthcare Co., Ltd, Shanghai, China

Three-dimensional variable-flip-angle (VFA) T1 mapping is a valuable T1 quantification method subject to a long scan time due to acquisition of multiple 3D images. SUPER (Shift Undersampling improves Parametric-mapping Efficiency and Resolution) is a recently developed method providing fast blockwise reconstruction for accelerated parametric mapping. Here we develop a combination of SUPER and 3D CAIPIRINHA to achieve 5-fold acceleration with 5 flip angles, validated with both retrospective and prospective reconstruction. The results suggest that the proposed method is highly accurate for accelerating 3D VFA T1 mapping, reducing the whole-brain scan time from 6 to 1.5 minutes.

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