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Abstract #2608

Discriminative Ensemble Average Propagator radial profiles along fixels of the centrum semiovale

Gabrielle Grenier1, François Rheault1,2, and Maxime Descoteaux1
1Sherbrooke Connectivity Imaging Lab (SCIL), Université de Sherbrooke, Sherbrooke, QC, Canada, 2Electrical Engineering, Vanderbilt University, Nashville, TN, United States

The Ensemble Average Propagator (EAP) encapsulates the angular and radial information of the diffusion magnetic resonance imaging (MRI) process and can highlight complex characteristics of the underlying tissue microstructure. Here, by sampling EAP values along different radii of the 3-way crossing of the centrum semiovale, we discriminate the orientations of the corticospinal tract from the arcuate fasciculus and the corpus callosum. This process finds microstructure signatures of fiber elements (fixels) of interest. Better tractometry as well as better local direction selection in tractography algorithms could be achieved with this information.

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