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Abstract #2717

Verifying the effect of DANTE preparation pulse for separating spin-compartments in arterial spin labeling using T2-measurement

Shota Ishida1, Hirohiko Kimura2, Naoyuki Takei3, Yasuhiro Fujiwara4, Tsuyoshi Matsuda5, Yuki Matta1, Masayuki Kanamoto1, Nobuyuki Kosaka2, and Eiji Kidoya1
1Radiological center, University of Fukui Hospital, Eiheiji, Japan, 2Department of Radiology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan, 3Global MR Applications and Workflow, GE Healthcare Japan, Hino, Japan, 4Department of Medical Image Sciences, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Japan, 5Division of Ultra-high Field MRI, Institute for Biomedical Science, Iwate Medical University, Shiwa-gun, Japan

To verify the characteristics of DANTE for vascular suppression, T2 values of the ASL signal under the application of DANTE were determined. While T2 values without DANTE decreased as the PLD increased, T2 values with DANTE (T2_DANTE) did not change among the PLDs. Moreover, T2_DANTE were equivalent to those of the reference. The positive correlation between T2 values and the ATT without DANTE was not observed when DANTE was used. T2_DANTE were neither dependent on the ATT nor PLD. Therefore, DANTE separates the spin compartments in ASL by selective elimination of intra-vascular signals from total ASL signals.

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