Abstract #2717

Verifying the effect of DANTE preparation pulse for separating spin-compartments in arterial spin labeling using T2-measurement

Shota Ishida¹, Hirohiko Kimura², Naoyuki Takei³, Yasuhiro Fujiwara⁴, Tsuyoshi Matsuda⁵, Yuki Matta¹, Masayuki Kanamoto¹, Nobuyuki Kosaka², and Eiji Kidoya¹

¹Radiological center, University of Fukui Hospital, Eiheiji, Japan, ²Department of Radiology, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan, ³Global MR Applications and Workflow, GE Healthcare Japan, Hino, Japan, ⁴Department of Medical Image Sciences, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Japan, ⁵Division of Ultra-high Field MRI, Institute for Biomedical Science, Iwate Medical University, Shiwa-gun, Japan

To verify the characteristics of DANTE for vascular suppression, T₂ values of the ASL signal under the application of DANTE were determined. While T₂ values without DANTE decreased as the PLD increased, T₂ values with DANTE (T_{2_DANTE}) did not change among the PLDs. Moreover, T_{2_DANTE} were equivalent to those of the reference. The positive correlation between T₂ values and the ATT without DANTE was not observed when DANTE was used. T_{2_DANTE} were neither dependent on the ATT nor PLD. Therefore, DANTE separates the spin compartments in ASL by selective elimination of intra-vascular signals from total ASL signals.

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