The goal of this study is to optimize and evaluate super-resolution simultaneous multislice (SMS) Arterial Spin Labeling (ASL) using the Slice Dithered Enhanced Resolution (SLIDER). Different numbers (2/3/4) of shifted slices for SLIDER SMS ASL were evaluated for spatial and temporal SNR. The results showed that the SNR efficiency of SLIDER SMS ASL increased with a greater number of shifted slices which may be attributed to reduced g-factor for SMS imaging of thicker slices as well as the presence of physiological noise.
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