Abstract #2729

Saturated Look-Locker FAIR (SALL-FAIR) Sequence with FPOCK Model for Simultaneous Acquisition of CBF, aBAT, tBAT, and T1 Map

Zihan Ning¹, Shuo Chen¹, Zhensen Chen¹, Huiyu Qiao¹, Hualu Han¹, Rui Shen¹, Dandan Yang¹, and Xihai Zhao¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine Tsinghua University, Beijing, China

A SAturated Look-Locker Flow-sensitive Alternating Inversion Recovery (SALL-FAIR) sequence combined with the Four-Phase One-Compartment Kety (FPOCK) kinetic model was proposed for simultaneous acquisition of CBF, aBAT, tBAT and T1 map with a single scan. The T1 maps of SALL-FAIR were verified by standard IR-SE on phantom, and higher accuracy of perfusion quantification from SALL-FAIR with FPOCK model was proved by comparing with the Buxton’s and the single-TI model in vivo.

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