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Abstract #2729

Saturated Look-Locker FAIR (SALL-FAIR) Sequence with FPOCK Model for Simultaneous Acquisition of CBF, aBAT, tBAT, and T1 Map

Zihan Ning1, Shuo Chen1, Zhensen Chen1, Huiyu Qiao1, Hualu Han1, Rui Shen1, Dandan Yang1, and Xihai Zhao1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine Tsinghua University, Beijing, China

A SAturated Look-Locker Flow-sensitive Alternating Inversion Recovery (SALL-FAIR) sequence combined with the Four-Phase One-Compartment Kety (FPOCK) kinetic model was proposed for simultaneous acquisition of CBF, aBAT, tBAT and T1 map with a single scan. The T1 maps of SALL-FAIR were verified by standard IR-SE on phantom, and higher accuracy of perfusion quantification from SALL-FAIR with FPOCK model was proved by comparing with the Buxton’s and the single-TI model in vivo.

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