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Abstract #2737

Robust Implementation of a 3D Pulsed ASL Sequence for Assessment of Liver Perfusion

Jörn Huber1, Daniel Hoinkiss1, and Matthias Günther1,2
1Fraunhofer MEVIS, Bremen, Germany, 2University of Bremen, Bremen, Germany

Liver perfusion can give valuable functional information about diseases like carcinoma and cirrhosis. Arterial Spin Labeling allows non-invasive assessment of liver perfusion without exogenous contrast agents being especially helpful in patients with renal failure. ASL in abdominal organs like liver faces increased challenges due to low perfusion rates, breathing motion and strong off-resonance as well as B1-inhomogeneity. In this work, a robust implementation of a pulsed ASL (PASL) sequence with FAIR labeling and 3D GRASE readout is provided, addressing these difficulties.

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