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Abstract #2747

Association of Arterial Spin Labeling Global Metrics and Attentional Processes

Shichun Chen1, Yakun Zhang1, Zongpai Zhang1, Wenna Duan1, George Weinschenk1, Brandon E. Gibb2, Wenming Luh3, and Weiying Dai1
1Department of Computer Science, State University of New York at Binghamton, Binghamton, NY, United States, 2Department of Psychology, State University of New York at Binghamton, Binghamton, NY, United States, 3National Institute on Aging, National Institutes of Health, Baltimore, MD, United States

We investigated the relationship between brain global activity or global topology of brain networks and attentional processes. The former measures were evaluated by dynamic arterial spin labeling (ASL) perfusion fMRI. The latter measures were assessed by P3 amplitude and latency in event-related potentials (ERPs). The P3 properties were significantly correlated with numbers of correct response. We found positive associations between global perfusion and P3 amplitude and between characteristic path length and P3 latency, and negative associations between global perfusion, global efficiency, mean functional connectivity and P3 latency, indicating close correlation of brain global behavior and attention.

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