Abstract #2747

Association of Arterial Spin Labeling Global Metrics and Attentional Processes

Shichun Chen¹, Yakun Zhang¹, Zongpai Zhang¹, Wenna Duan¹, George Weinschenk¹, Brandon E. Gibb², Wenming Luh³, and Weiying Dai¹

¹Department of Computer Science, State University of New York at Binghamton, Binghamton, NY, United States, ²Department of Psychology, State University of New York at Binghamton, Binghamton, NY, United States, ³National Institute on Aging, National Institutes of Health, Baltimore, MD, United States

We investigated the relationship between brain global activity or global topology of brain networks and attentional processes. The former measures were evaluated by dynamic arterial spin labeling (ASL) perfusion fMRI. The latter measures were assessed by P3 amplitude and latency in event-related potentials (ERPs). The P3 properties were significantly correlated with numbers of correct response. We found positive associations between global perfusion and P3 amplitude and between characteristic path length and P3 latency, and negative associations between global perfusion, global efficiency, mean functional connectivity and P3 latency, indicating close correlation of brain global behavior and attention.

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