Abstract #2752

Prostate Perfusion Mapping using Fourier-Transform based Velocity-Selective Pulse Trains: Choice of Cutoff Velocity and Comparison with Brain

Dapeng Liu^1,2, Dan Zhu³, Wenbo Li^1,2, and Qin Qin^1,2

¹Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, ²F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, ³Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States

Prostate perfusion mapping using velocity-selective arterial spin labeling (VSASL) is desired for higher SNR and insensitivity to arterial transit delay. The choice of cutoff velocity (Vc) determines its sensitivity to perfusion-weighted signal (PWS). The utility of Fourier-transform based velocity-selective (FT-VS) pulse trains have been demonstrated in cerebral blood flow and cerebral blood volume mapping. In this study, FT-VS prepared blood flow and blood volume mapping sequences were performed in parallel in both brain and prostate to investigate their Vc dependence to PWS. The results suggest that lower Vc is demanded for prostate VSASL.

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