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Abstract #2765

Distinction of early fibrosis stages in patients with chronic hepatitis B using intra voxel incoherent motion MR imaging

Hongyi Li1, Weiyin Vivian Liu2, Lesheng Huang1, Tianzhu Liu1, Jinghua Jiang1, Wanchun Zhang1, Jiahui Tang1, Tao He1, and Jun Chen1
1Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, 2MR Research, GE Healthcare, Beijing, China, Beijing, China

The purpose was to evaluate the feasibility of IVIM variables in distinction of patients with early liver fibrosis stages(F1-2). Eight volunteers and 21 patients suspected chronic hepatitis B with fibrosis stage F1 or F2 were recruited. Correlations between all IVIM and DWI variables and ALT, AST, GGT values were analyzed. Two-segment mono-exponential model derived Dslow,TM was statistically different between volunteers and F1 patients(p< 0.05) with AUC of 0.740. The correlation between bi-exponential model derived Dslow,B and GGT was fair(r =0.513, p < 0.05).

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