The purpose was to evaluate the feasibility of IVIM variables in distinction of patients with early liver fibrosis stages(F1-2). Eight volunteers and 21 patients suspected chronic hepatitis B with fibrosis stage F1 or F2 were recruited. Correlations between all IVIM and DWI variables and ALT, AST, GGT values were analyzed. Two-segment mono-exponential model derived Dslow,TM was statistically different between volunteers and F1 patients(p< 0.05) with AUC of 0.740. The correlation between bi-exponential model derived Dslow,B and GGT was fair(r =0.513, p < 0.05).