Abstract #2765

Distinction of early fibrosis stages in patients with chronic hepatitis B using intra voxel incoherent motion MR imaging

Hongyi Li¹, Weiyin Vivian Liu², Lesheng Huang¹, Tianzhu Liu¹, Jinghua Jiang¹, Wanchun Zhang¹, Jiahui Tang¹, Tao He¹, and Jun Chen¹

¹Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, China, ²MR Research, GE Healthcare, Beijing, China, Beijing, China

The purpose was to evaluate the feasibility of IVIM variables in distinction of patients with early liver fibrosis stages(F1-2). Eight volunteers and 21 patients suspected chronic hepatitis B with fibrosis stage F1 or F2 were recruited. Correlations between all IVIM and DWI variables and ALT, AST, GGT values were analyzed. Two-segment mono-exponential model derived D_slow,TM was statistically different between volunteers and F1 patients(p< 0.05) with AUC of 0.740. The correlation between bi-exponential model derived D_slow,B and GGT was fair(r =0.513, p < 0.05).

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