Abstract #2776

Free-Breathing, 3D Phase Sensitive Inversion Recovery MRI with Stack-of-Stars SGRE and Locally Low Rank Reconstruction

Yavuz Muslu^1,2, Ty A. Cashen³, Sagar Mandava⁴, and Scott B. Reeder^1,2,5,6,7

¹Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Global MR Applications and Workflow, GE Healthcare, Madison, WI, United States, ⁴Global MR Applications and Workflow, GE Healthcare, Atlanta, GA, United States, ⁵Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁷Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Gadoxetic acid (GA)-enhanced MRI is an important tool for the detection of liver metastases. Through GA dose optimization and novel pulse sequence strategies, small lesions are often resolved using only high resolution GA-enhanced hepatobiliary phase T1w-MRI. However, such small lesions are often occult in T2w, diffusion weighted imaging (DWI) and dynamic contrast enhanced (DCE) T1w-MRI, which hinders the ability of MRI to characterize these lesions. In this work, we propose the development of a phase sensitive inversion recovery (PSIR) T1w-MRI in combination with 3D radial stack-of-stars imaging for detection and characterization of small focal liver lesions.

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