High spatiotemporal resolution DCE-MRI has great clinical value in disease diagnosis and treatment. In this study, we propose to use a video block matching 3-D filtering approach to improve high spatiotemporal resolution DCE-MRI. Both phantom and in vivo experiments were performed in this work. The phantom experiment indicated that the proposed approach outperforms iGRASP and GRASP-Pro methods with lower reconstruction errors, especially in cases involving super high reduction factors. In vivo experiments draw similar conclusion. This new technique can provide a potential solution for real-time imaging and image guided radiation therapy.
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