Abstract #2831

Reproducibility of Semi-LASER Localized Correlated Spectroscopic Imaging Using Concentric Ring Echo-Planar Trajectories

Andres Saucedo¹, Manoj Kumar Sarma¹, Uzay Emir², James Sayre¹, Paul M Macey³, and Michael Albert Thomas¹

¹Radiological Sciences, UCLA Geffen School of Medicine, Los Angeles, CA, United States, ²School of Health Sciences, Purdue University, West Lafayette, IN, United States, ³UCLA School of Nursing, Los Angeles, CA, United States

Five-dimensional correlated spectroscopic imaging using concentric ring trajectories (5D COSI-CONCEPT) has been implemented. Since the maximum slew rates required for the concentric ring trajectories are lower than those for Cartesian echo-planar spectroscopic imaging for a given spectral bandwidth and spatial resolution, the eddy current issues are less challenging. The acquired 5D COSI-CONCEPT data was regridded along k_x-k_y and the accelerated k_z-t₁ data was reconstructed using group sparsity. Reproducibility of the sequence was evaluated in a brain phantom using 3T Prisma and Skyra MRI scanners. Pilot findings showed excellent coefficients of variance and intra-class correlation coefficients for all the six metabolites.

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