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Abstract #2852

Time resynchronization of data obtained during cardiovascular MRI combined with catheterization using biophysical cardiac modeling

Maria Gusseva1,2, Daniel Alexander Castellanos3, Mohamed Abdelghafar Hussein4,5, Joshua Greer 4, Gerald Greil4, Surendranath Veeram Reddy4, Dominique Chapelle1,2, Tarique Hussain4, and Radomir Chabiniok1,2,4,6
1Inria, Palaiseau, France, 2LMS, Ecole Polytechnique, Palaiseau, France, 3Department of Cardiology, Boston Children’s Hospital, Boston, MA, United States, 4Division of Pediatric Cardiology, UT Southwestern Medical Center Dallas, Dallas, TX, United States, 5Pediatric department, Kafrelsheikh University, Kafr Elsheikh, Egypt, 6Department of Mathematics, Czech Technical University in Prague, Faculty of Nuclear Sciences and Physical Engineering, Prague, Czech Republic

Time resynchronization of data is often needed when the analysis is based on combining several cardiovascular MRI (CMR) sequences and/or when CMR is combined with a different modality such as pressure catheter during interventional CMR (iCMR). In the present work we propose using patient-specific biophysical model to resynchronize the intraventricular pressure and volume data. The model-driven resynchronization strategy generates pressure-volume (P-V) loops, which can be then used for clinical interpretation. Moreover, the patient-specific model provides additional mechanical indicators of patient's physiology. This framework has the perspective to contribute to planning of complex surgical interventions.

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