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Abstract #2882

3D DCE MRI of carotid plaque by dynamic T1 mapping using Single Reference Variable Flip Angle 3D Pseudo Golden Angle Stack of Stars Acquisition

Seong-Eun Kim1, J Scott McNally1, John A Roberts1, Matthew Alexander 1, Hediyeh Baradaran 1, Gerald S Treiman2, and Dennis L Parker1
1UCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 2Department of Veterans Affairs, VASLCHCS, Salt Lake City, UT, United States

Dynamic contrast‐enhanced (DCE) MRI has been used for quantitative assessment of the neovascular architecture and perfusion properties in the carotid artery wall5. While DCE-MRI has great potential in plaque component characterization, it is presently limited by SNR, contrast, available resolution, and motion artifacts for carotid plaque application. In this work, we propose a new dynamic MRI method capable of high spatial and temporal resolution, and dynamic T1 mapping-based quantification of contrast agent concentration for the assessment of carotid intraplaque hemorrhage to overcome the barriers that prevent DCE-MRI from being the clinical standard for carotid IPH evaluation.

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