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Abstract #2884

In Vivo Aortic MR Elastography in Abdominal Aortic Aneurysm Patients: A Potential Biomarker for Predicting Aneurysmal Events

Huiming Dong1,2, Brian Raterman1, Mariah Eisner3, Guy Brock3, Richard D White1, Jean Starr4, Mounir Haurani4, Michael Go4, Patrick Vaccaro4, and Arunark Kolipaka1,2
1Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States, 2Biomedical Engineering, The Ohio State University, Columbus, OH, United States, 3Biomedical Informatics, The Ohio State University Wexner Medical Center, Columbus, OH, United States, 4Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States

Abdominal aortic aneurysm (AAA) can result in life-threatening rupture. AAA diameter remains the only clinically useful parameter to predict growth and rupture risk. However, some high-risk AAAs can be overlooked due to their small diameters. AAA stiffness is associated with its extracellular matrix remodeling and thus potentially provides more relevant rupture prediction. Therefore, this study aims to estimate AAA stiffness using aortic MRE in patients with and without aneurysmal events. This is the first study to demonstrate that AAA stiffness and AAA/remote normal (AAA/RN) stiffness ratio are significantly lower in patients with aneurysmal events.

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