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Abstract #2932

Monaural auditory stimulation induces negative BOLD in the rat auditory pathway

Frederico Severo1, Rita Gil1, and Noam Shemesh1
1Champalimaud Centre for the Unknown, Lisboa, Portugal

fMRI has been used to characterize the auditory pathway in rodents in the past, but unlike other modalities, these studies haven’t shown any prominent negative responses in any structure along the auditory pathway. Our findings reveal, for the first time, negative BOLD signals induced by monaural stimulation with broadband white noise in the ipsilateral inferior colliculus and contralateral striatum. These findings may shed light into the intercollicular dynamics in sound processing in the rat brain upon, e.g., sound localization or spatial navigation.

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