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Abstract #2951

The value of magnetic resonance T2*mapping for early detection of knee cartilage damage in hemophilia arthropathy

Jiajia Li1, Shufang Wei1, Xianchang Zhang2, Jing An3, and Yinghui Ge1
1Fuwai Central China Cardiovascular Hospital, Zhengzhou, China, 2MR Collaboration, Siemens Healthcare Ltd., Beijing, China, Beijing, China, 3Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China

Early detection and therapy of articular cartilage damage are key to the management of hemophilia arthropathy (HA). Magnetic resonance (MR) T2* mapping has been used to detect iron deposits in the brain and liver but rarely in HA. We compared T2*mapping results of 15 HA patients (18 knees) and 10 volunteers (18 knees). We found that the average T2* values of the medial femoral condyle and medial tibial plateau cartilage in HA patients were significantly lower than in the normal group, suggesting the importance of T2* mapping in the quantitative assessment of iron deposition for early cartilage damage diagnosis in HA patients.

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