Early detection and therapy of articular cartilage damage are key to the management of hemophilia arthropathy (HA). Magnetic resonance (MR) T2* mapping has been used to detect iron deposits in the brain and liver but rarely in HA. We compared T2*mapping results of 15 HA patients (18 knees) and 10 volunteers (18 knees). We found that the average T2* values of the medial femoral condyle and medial tibial plateau cartilage in HA patients were significantly lower than in the normal group, suggesting the importance of T2* mapping in the quantitative assessment of iron deposition for early cartilage damage diagnosis in HA patients.
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