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Abstract #2956

Deep Cartilage UTE-T2* Shows Compositional Heterogeneity in Patients with Degenerative Meniscus Tears

Ashley A. Williams1,2, Karyn E. Chappell1,2, and Constance R. Chu1,2
1Orthopaedic Surgery, Stanford University, Stanford, CA, United States, 2Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, United States

This study evaluated deep cartilage and meniscus UTE-T2* against spatially targeted arthroscopic assessments in patients with degenerative meniscus tears to further inform interpretation and utility of in vivo UTE-T2* for different degrees of pathology. While arthroscopic evaluation confirmed that UTE-T2* was elevated in menisci with degenerative fraying and tears, increasing intra-operative cartilage grade was not associated with strictly increasing cartilage UTE-T2*. Instead, in osteoarthritic disease states where the articular surface of cartilage is disrupted, this report suggests that mono-exponential deep cartilage UTE-T2* may not be a reliable indicator of tissue pathology.

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