This study evaluated deep cartilage and meniscus UTE-T2* against spatially targeted arthroscopic assessments in patients with degenerative meniscus tears to further inform interpretation and utility of in vivo UTE-T2* for different degrees of pathology. While arthroscopic evaluation confirmed that UTE-T2* was elevated in menisci with degenerative fraying and tears, increasing intra-operative cartilage grade was not associated with strictly increasing cartilage UTE-T2*. Instead, in osteoarthritic disease states where the articular surface of cartilage is disrupted, this report suggests that mono-exponential deep cartilage UTE-T2* may not be a reliable indicator of tissue pathology.
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