Abstract #3032

Evaluation and Quantification of SWI MRA of Cerebral Vasculature in Parkinson’s Disease Patients

Dmytro Pylypenko¹, Yuhui Xiong¹, Lanxin Ji¹, Le He¹, Yu Ma², and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, ²Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing, China

This study aimed to perform an evaluation of the vascular geometry in PD patients vs. healthy control group to quantify the structural changes in the cerebral vasculature by analyzing SWI MRA data. Findings show, that the PD’s vasculature network was found to have a higher tortuosity, fractality, and branching, yet lower volume and total length as well as smaller average diameter. It is also important to state that aging has a great impact on vascular impairment in PD patients.

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