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Abstract #3050

Simultaneous Mapping of Metabolite Concentration and T1 Relaxation Time Using Subspace Imaging Accelerated Inversion Recovery MRSI

Chao Ma1,2, Paul K. Han1,2, and Georges El Fakhri1,2
1Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Radiology, Harvard Medical School, Boston, MA, United States

Absolution quantification of metabolite concentration requires accurate measurement of the longitudinal relaxation times of metabolites. However, it will be very time consuming to access the spatial variations of metabolite T1 relaxation times using the conventional MRS-based methods. Inspired by the recent success of the subspace-based methods for fast high-resolution MRSI, we propose a subspace imaging-based method for simultaneous mapping of metabolite concentration and T1 relaxation time. We propose a fast Look-Locker EPSI sequence for data acquisition and a low-rank tensor-based method for simultaneous reconstruction of MRSI images at different TIs.

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