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Abstract #3058

Ultra-high Spatial Resolution Multispectral qMRI with Compressed Sensing Tri-TSE

Ryan McNaughton1, Hernan Jara1,2, Ning Hua2,3, Andy Ellison2,3, Lee Goldstein1,2,3, and Stephan Anderson2,3
1Boston University, Boston, MA, United States, 2Boston University Medical Center, Boston, MA, United States, 3Center for Translational Neuroimaging, Boston, MA, United States

Purpose: To test the PD-T1-T2 qMRI accuracy of ultra-high spatial resolution compressed sense Tri-TSE. Methods: A healthy male volunteer (35yo) was scanned with an ultra-high spatial resolution compressed sensing Tri-TSE pulse sequence. Maps of PD, T1, and T2 were generated with voxel size of 0.4 x 0.4 x 1.2 mm3. Results: PD, T1, and T2 accuracy are not affected by threefold compressed sensing acceleration. Conclusion: Compressed sensing does not appear to negatively impact MS-qMRI accuracy and opens the door to ultrafast brain MS-qMRI at current clinical spatial resolution or to a new high spatial resolution standard in the clinical context.

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