Abstract #3067

Asymmetries in the distribution of quantitative MRI parameters in the brain

Jonas Kielmann*¹, Ana-Maria Oros-Peusquens*¹, Nora Bittner², Svenja Caspers², and N. Jon Shah^1,3,4,5

¹INM-4, Research Centre Juelich, Juelich, Germany, ²INM-1, Research Centre Juelich, Juelich, Germany, ³Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany, ⁴INM-11, JARA, Research Centre Juelich, Juelich, Germany, ⁵Department of Neurology, RWTH Aachen University, Aachen, Germany

Multicontrast quantitative MRI is used to characterize left-right and sulcal-gyral asymmetries of the brain in 26 volunteers. Several regions with significant asymmetries are found in different parameters (H2O, fbound, R2*, R1, kex, QSM). Good correlation between sulcal-gyral H2O-defined asymmetry and local gyrification index is found.

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