The gold standard T1 mapping method is the Inversion Recovery (IR). Volumetric sequences such as MP2RAGE without or with compressed sensing (csMP2RAGE) allow faster T1-mapping, but potential biases are not well characterized. Here we investigated T1-mapping and test-retest reproducibility effects of sequence (IR, MP2RAGE, csMP2RAGE) and head RF coil (64 and 20-channel), both in-vitro and in-vivo. The 64-channel coil results are more accurate and reliable, showing good agreement with the gold standard and a beneficial reduction of scan time.
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