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Abstract #3072

Isotropic T1-mapping of the whole brain by MP-RAGE at different inversion times

Gunther Helms1 and Hampus Olsson1
1Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden

Fitting the inversion recovery (IR) at multiple TI provides T1 estimates of high accuracy if performed in a single slice with full relaxation. We present an isotropic 3D variant based on MP-RAGE, where a T1-weighted driven equilibrium is prepared prior to inversion by a second RAGE readout. This abolishes the need for long recovery times and provides volumes of similar contrast for co-registration. The method was tested at 3T on a small cohort and compared to 3D IR-TSE and 3D variable flip angle mapping.

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