Abstract #3071

Diffusion sensitivity of spin echo sequences affects white matter R2 fiber orientation dependency

Christoph Birkl¹, Christian Kremser², Alexander Rauscher³, and Elke Ruth Gizewski¹

¹Department of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria, ²Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria, ³UBC MRI research Centre, University of British Columbia, Vancouver, BC, Canada

We investigated how the sensitivity of spin-echo and turbo spin echo MRI sequences to diffusion processes affects the estimation of fiber orientation dependent R2 in white matter. Our results indicate that the strongest R2 orientation dependency is observed when R2 is estimated using multiple single spin echo sequences. The lowest R2 orientation dependency was observed for the multi-echo spin echo sequence.

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