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Abstract #3104

D-T2 Distribution Obtained Using CPMG-only Sequence Compared with Traditional SE-CPMG Sequence on the Single-sided NMR Device

Ziyi Pan1, Jieying Zhang1, Hai Luo2, Weiqian Wang2, Xiao Chen2, Ziyue Wu2, and Hua Guo1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Marvel Stone Healthcare, Wuxi, Jiangsu, China

Two-dimension (2D) diffusion-relaxation (D-T2) correlation measured by a low-cost, portable single-sided NMR system can separate fat and water in biological tissues (for example for liver steatosis detection). Diffusion-editing CPMG sequence is commonly used for such measurement. Recently, a novel approach is proposed to measure the D-T2 correlation using the simplest CPMG-only sequence. The CPMG-only sequence is less sensitive to motion, and can extend to systems with more imperfect magnetic and radiofrequency fields. This work compares the proposed CPMG-only sequence with the traditional diffusion-editing SE-CPMG sequence. Results show the SE-CPMG and CPMG-only sequences can achieve comparable performance on water-fat separation.

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