Abstract #3104

D-T2 Distribution Obtained Using CPMG-only Sequence Compared with Traditional SE-CPMG Sequence on the Single-sided NMR Device

Ziyi Pan¹, Jieying Zhang¹, Hai Luo², Weiqian Wang², Xiao Chen², Ziyue Wu², and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Marvel Stone Healthcare, Wuxi, Jiangsu, China

Two-dimension (2D) diffusion-relaxation (D-T₂) correlation measured by a low-cost, portable single-sided NMR system can separate fat and water in biological tissues (for example for liver steatosis detection). Diffusion-editing CPMG sequence is commonly used for such measurement. Recently, a novel approach is proposed to measure the D-T₂ correlation using the simplest CPMG-only sequence. The CPMG-only sequence is less sensitive to motion, and can extend to systems with more imperfect magnetic and radiofrequency fields. This work compares the proposed CPMG-only sequence with the traditional diffusion-editing SE-CPMG sequence. Results show the SE-CPMG and CPMG-only sequences can achieve comparable performance on water-fat separation.

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