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Abstract #3125

Investigating the relationship between temporal SNR and resting-state networks to evaluate the feasibility of fMRI at a low field MR scanner

Arjama Halder1,2, Demetrius Riberio de Paula3, William B Handler1, Andrea Soddu1, and Blaine A Chronik1,2
1xMR Labs, Physics and Astronomy, Western University, London, ON, Canada, 2Medical Biophysics, Western University, London, ON, Canada, 3Donders Institute, Radbound University, Nijmegen, Netherlands

This preliminary investigation evaluates the feasibility of resting-state BOLD fMRI at a 0.5T MR scanner equipped with a high-performance gradient coil. Here, we evaluated the decrement in the number of extracted resting-state networks as tSNR decreased with reduced scanner field strength. The results from this study suggest a positive linear relationship between the calculated correlation coefficients for different resting-state networks and tSNR within a 95% confidence interval. A lower limit on the tSNR at which the networks are detectable can be calculated from this analysis and will be used in experimental studies with the 0.5T scanner.

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