Abstract #3125

Investigating the relationship between temporal SNR and resting-state networks to evaluate the feasibility of fMRI at a low field MR scanner

Arjama Halder^1,2, Demetrius Riberio de Paula³, William B Handler¹, Andrea Soddu¹, and Blaine A Chronik^1,2

¹xMR Labs, Physics and Astronomy, Western University, London, ON, Canada, ²Medical Biophysics, Western University, London, ON, Canada, ³Donders Institute, Radbound University, Nijmegen, Netherlands

This preliminary investigation evaluates the feasibility of resting-state BOLD fMRI at a 0.5T MR scanner equipped with a high-performance gradient coil. Here, we evaluated the decrement in the number of extracted resting-state networks as tSNR decreased with reduced scanner field strength. The results from this study suggest a positive linear relationship between the calculated correlation coefficients for different resting-state networks and tSNR within a 95% confidence interval. A lower limit on the tSNR at which the networks are detectable can be calculated from this analysis and will be used in experimental studies with the 0.5T scanner.

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