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Abstract #3134

Deep Linear Modeling of Hierarchical Functional Connectivity in the Human Brain

Wei Zhang1, Eva M Palacios1, and Pratik Mukherjee1
1UCSF, San Francisco, CA, United States

To better map hierarchical brain connectivity networks, we introduce a novel class of deep (multilayer) linear models of fMRI that bridge the gap between conventional methods such as independent component analysis and more complex deep nonlinear models. These deep linear models do not require the manual hyperparameter tuning, extensive fMRI training data or high-performance computing infrastructure needed by deep learning, such as convolutional neural networks, and their results are more explainable from their mathematical structure. These benefits gain in importance as continual improvements in the spatial and temporal resolution of fMRI reveal more of the hierarchy of spatiotemporal brain architecture.

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