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Abstract #3196

Multimodal MRI evaluation of paraspinal muscles and TNF- α in rats with discogenic low back pain after rehabilitation training

Kaiwen Yang1, Baofa Luo1, Yilong Huang1, Lisha Nie2, and Bo He1
1Medical imaging department, The First Affiliated Hospital of Kunming Medical University, Kunming, China, 2GE Healthcare,MR Research China, Beijing, China

Based on functional MRI, the current study aims to explore the pathological morphology, fat infiltration and the expression of TNF-α in paraspinal muscles of discogenic low back pain(DLBP). And to further explore the relation of rehabilitation exercise on paraspinal muscles and intervertebral discs in rats. It is concluded that rehabilitation exercise can reduce the content of TNF-α in serum and paraspinal muscles, relieve the symptoms of DLBP in rats, and improve paraspinal muscle dysfunction.

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