Abstract #3196

Multimodal MRI evaluation of paraspinal muscles and TNF- α in rats with discogenic low back pain after rehabilitation training

Kaiwen Yang¹, Baofa Luo¹, Yilong Huang¹, Lisha Nie², and Bo He¹

¹Medical imaging department, The First Affiliated Hospital of Kunming Medical University, Kunming, China, ²GE Healthcare,MR Research China, Beijing, China

Based on functional MRI, the current study aims to explore the pathological morphology, fat infiltration and the expression of TNF-α in paraspinal muscles of discogenic low back pain(DLBP）. And to further explore the relation of rehabilitation exercise on paraspinal muscles and intervertebral discs in rats. It is concluded that rehabilitation exercise can reduce the content of TNF-α in serum and paraspinal muscles, relieve the symptoms of DLBP in rats, and improve paraspinal muscle dysfunction.

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