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Abstract #3197

DCE-MRI for the Assessment of Outcome of CyberKnife Stereotactic Radiosurgery for Patients with Spinal Metastases

Yongye Chen1, Enlong Zhang 2, Qizheng Wang 1, Huishu Yuan1, Huishu Yuan1, Hongqing Zhuang1, and Ning Lang1
1Peking University Third Hospital, Beijing, China, 2Peking University International Hospital, Beijing, China

The imaging methods used to evaluate the efficacy of radiosurgery in spinal metastases have certain limitations. DCE-MRI can help determine the vascularity and hemodynamics of tumors in vivo, and can be used to evaluate local tumor response. Twenty-seven patients with 39 lesions were included. Post-treatment Kep, ΔKtrans and ΔKep in the non-progressive disease group were significantly lower than the corresponding values in progressive disease group. Post-treatment Ve and ΔVe in the non-progressive disease group were significantly higher than that of the progressive disease group. ΔKtrans had the highest diagnostic efficiency, with an AUC of 0.821.

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