The imaging methods used to evaluate the efficacy of radiosurgery in spinal metastases have certain limitations. DCE-MRI can help determine the vascularity and hemodynamics of tumors in vivo, and can be used to evaluate local tumor response. Twenty-seven patients with 39 lesions were included. Post-treatment Kep, ΔKtrans and ΔKep in the non-progressive disease group were significantly lower than the corresponding values in progressive disease group. Post-treatment Ve and ΔVe in the non-progressive disease group were significantly higher than that of the progressive disease group. ΔKtrans had the highest diagnostic efficiency, with an AUC of 0.821.