19F-MRI of inhaled perfluoropropane (PFP) permits regional assessment of pulmonary ventilation. Dynamic multi-breath PFP wash-in and wash-out images were acquired in one healthy volunteer and two patients with chronic obstructive pulmonary disease (COPD) during short successive breath holds, using a repeated 3D 19F-SPGR sequence accelerated with compressed sensing. Resultant image quality achieved in each 7.5s compressed sensing acquisition dynamic was sufficient for segmentation and permitted visualisation of a case of gas trapping secondary to apical predominant emphysema. A strong negative correlation between regional wash-in and wash-out rates and spirometric indices was measured.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords