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Abstract #3228

A 3D Stack-of Spirals Approach for Inert Fluorinated (19F) Gas MRI of the Lungs

Brandon Zanette1, Yonni Friedlander1,2, Marcus J Couch3,4,5, and Giles Santyr1,2
1Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Siemens Healthcare Limited, Montreal, QC, Canada, 4McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, QC, Canada, 5Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada

Inert fluorinated (19F) gas MRI is an emergent technology that has potential to be a lower cost, reduced infrastructure alternative to hyperpolarized gas MRI for lung imaging. In this work we present an approach for non-Cartesian spiral imaging in a phantom. Compared to typical gradient echo imaging with the same spatial resolution, the proposed approach increased SNR by 44% in approximately a third of the acquisition time. Further simulation and extrapolation to clinical imaging experiments indicate significant potential for this approach to improve SNR and image quality.

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