Abstract #3228

A 3D Stack-of Spirals Approach for Inert Fluorinated (19F) Gas MRI of the Lungs

Brandon Zanette¹, Yonni Friedlander^1,2, Marcus J Couch^3,4,5, and Giles Santyr^1,2

¹Translational Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, ³Siemens Healthcare Limited, Montreal, QC, Canada, ⁴McConnell Brain Imaging Centre, Montreal Neurological Institute, Montreal, QC, Canada, ⁵Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada

Inert fluorinated (¹⁹F) gas MRI is an emergent technology that has potential to be a lower cost, reduced infrastructure alternative to hyperpolarized gas MRI for lung imaging. In this work we present an approach for non-Cartesian spiral imaging in a phantom. Compared to typical gradient echo imaging with the same spatial resolution, the proposed approach increased SNR by 44% in approximately a third of the acquisition time. Further simulation and extrapolation to clinical imaging experiments indicate significant potential for this approach to improve SNR and image quality.

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