Abstract #3229

Simulation of Lung Parenchyma MRI and Field-Strength Dependence

Bochao Li¹, Nam G. Lee¹, and Krishna Nayak²

¹Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, ²Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, United States

MRI of lung parenchyma is limited by low proton density and susceptibility effects at air-tissue interfaces. Recent high-performance low-field MRI systems have provided a new opportunity to mitigate the latter issue. In this work, we demonstrate a framework for simulating lung MRI across B0 field strengths. We estimate apparent transverse relaxation due to proximity to A) sub-voxel alveoli, and B) bronchial tree. Alveoli are modeled using face-centered cubic close packing. The bronchial tree is modeled using a recent XCAT phantom.

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