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Abstract #3279

Using MRI and Radiomics to Predict Pain in a Cohort of Trigeminal Neuralgia Patients Treated With Radiosurgery

Kellen Mulford1, Sean Moen2, Andrew W. Grande2, Donald R. Nixdorf3, and Pierre-Francois Van de Moortele1
1Center for Magnetic Resonance Imaging, University of Minnesota, Minneapolis, MN, United States, 2Department of Neurosurgery, University of Minnesota, Minneapolis, MN, United States, 3Department of Diagnostic and Biological Science, University of Minnesota, Minneapolis, MN, United States

Due to a lack of objective markers, trigeminal neuralgia is difficult to diagnose and classify. This difficulty results in frequent pain recurrences following medication and invasive therapies. In this work, we show that a radiomics based model with features extracted from MRI images can be used to identify painful nerves. Using a cohort of trigeminal neuralgia patients, our predictive model achieves an accuracy of 78% and an AUC of 0.84 in distinguishing between nerves affected and nonaffected by trigeminal neuralgia.

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