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Abstract #3288

Optimization of Spoiled GRE-based IR Acquisition Scheme for 3D Cardiac T1 Mapping at 3T

Paul Han1, Thibault Marin1, Vanessa Landes2, Yanis Djebra1,3, Georges El Fakhri1, and Chao Ma1
1Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, 2GE Healthcare, Boston, MA, United States, 3LTCI, Télécom Paris, Institut Polytechnique de Paris, Paris, France

Spoiled gradient echo (GRE) is an attractive alternative to balanced steady-state free precession (bSSFP) for ECG-gated recovery (IR)-based volumetric myocardial T1 mapping at 3T. However, the robustness of T1 estimation from spoiled GRE-based ECG-gated IR acquisitions has not been thoroughly investigated under different schemes and in the presence of B1 inhomogeneity. This work investigated effects of B1 inhomogeneity in the context of T1 estimation, considering B1 inhomogeneity in the model for T1 estimation, and characterized effects of flip angle and heart rate to optimize a spoiled GRE-based ECG-gated IR acquisition scheme for 3D cardiac T1 mapping.

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