Abstract #3288

Optimization of Spoiled GRE-based IR Acquisition Scheme for 3D Cardiac T1 Mapping at 3T

Paul Han¹, Thibault Marin¹, Vanessa Landes², Yanis Djebra^1,3, Georges El Fakhri¹, and Chao Ma¹

¹Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States, ²GE Healthcare, Boston, MA, United States, ³LTCI, Télécom Paris, Institut Polytechnique de Paris, Paris, France

Spoiled gradient echo (GRE) is an attractive alternative to balanced steady-state free precession (bSSFP) for ECG-gated recovery (IR)-based volumetric myocardial T₁ mapping at 3T. However, the robustness of T₁ estimation from spoiled GRE-based ECG-gated IR acquisitions has not been thoroughly investigated under different schemes and in the presence of B₁ inhomogeneity. This work investigated effects of B₁ inhomogeneity in the context of T₁ estimation, considering B₁inhomogeneity in the model for T₁ estimation, and characterized effects of flip angle and heart rate to optimize a spoiled GRE-based ECG-gated IR acquisition scheme for 3D cardiac T₁ mapping.

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